MAP Tau, htau40, 2N4R, with 441 amino acids runs heavy on SDS-PAGE. What can explain a 22 kDa difference in actual vs apparent?

MAP Tau, htau40, 2N4R, has the actual weight of 45 kDa but runs as 67 kDa on SDS-PAGE. What can explain this much weight difference? Is it specifically about Tau's unique structure effecting...

14 July 2023 3,748 1 View