Luca Avenali

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Questions related from Luca Avenali

Has anyone tried or heard of injection of CRISPR/Cas9 plasmid in adult mice as an alternative to siRNA to knock-down genes in developed animals?

Would intrathecal administration of a bicistronic plasmid coding for my target gene and cas9 nuclease lead to any outcome to your knowledge? Many thanks in advance

06 June 2015 9,521 2 View

Is anyone familiar with inducible mouse lines with Crispr/Cas9 systems?

Hi, we just planned to make a KO mouse line for a protein we're studying. The ideal would be a conditional and inducible one. Has anyone experience with that? Would that be feasible at all with...

02 February 2015 3,960 5 View