Bursting of DA neurons mobilized DA reserve pools in the terminals. This may produce dyskinesia. Could alpha2 antagonists target this via Ca?

We found that stimulation of the DA pathways in bursts reorganized DA storage pools. See: Role of alpha-synuclein in presynaptic dopamine recruitment.Yavich L, et al. J Neurosci. 2004. How DA...

02 February 2017 7,157 1 View