Leonard Amaral

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Questions related from Leonard Amaral

Thioridazine cures mice of antibiotic susceptible and MDR TB infections and cures XDR TB patients so why not use it now?

Thioridazine is cheap, and it inhibits the replication of all encountered Mtb strains regardless of their antibiotic resistance status , it enhances intracellular killing of MDR Mtb and XDR Mtb ,...

28 November 2013 2,979 2 View

Are those infected Mtb human subjects that do not develop active disease infected with a benign strain?

Strangely enough, the isolation of Mtb and analysis of its genome from autopsy subjects who do not present with active disease, has not been a subject of investigation. Because a parasite does not...

15 November 2013 5,767 36 View

Are efflux pumps of bacteria the means by which all secretions from the bacterium take place?

The first response of bacteria to a noxious agent such as an antibiotic is the induced over expression of efflux pumps. Once the threat of the noxious agent passes, the level of efflux pump...

28 June 2013 2,732 4 View

Can specific lasers matched to the energy level of a molecule create new molecules not readily made by conventional organic chemistry methods?

We have exposed a number of bioactive pure compounds to lasers of a given nm wavelength and energy level for varying periods of time, followed the result of exposure via thin layer chromatography,...

28 May 2013 509 1 View