Kadja Chagas

3 Questions 5 Answers 0 Followers

Questions related from Kadja Chagas

Free thiol in structure, how to proceed for amide coupling?

I'm trying to do a coupling reaction between a carboxylic acid and an amine. However, my acid has a free thiol group in the structure, which I cannot remove. Is there any selective coupling agent...

15 February 2024 5,953 0 View

How can I automatically screen compounds in a docking library that have made specific interactions with a residue?

I'm working on a virtual screen of approximately 8000 compounds, and I need to select only those that interact specifically with an active site residue. However, it is clearly impossible to...

24 April 2023 9,690 0 View

How can I remove aldehyde from a schiff base reaction?

I tried the synthesis of several aromatic aldehydes with 5-aminoindole, however, the reagents are not completely consumed and I have great difficulty in removing the aldehyde by chromatography....

28 May 2020 3,045 14 View