Joseph Hannon Bozorgmehr

6 Questions 10 Answers 0 Followers

Questions related from Joseph Hannon Bozorgmehr

Are "de novo" genes, that have no counterparts, just cases of homology detection failure?

In recent years, a slew of papers have been published claiming that many lineage-specific genes, lacking homologs, arose from non-genic sequences. However, a disclaimer is always made that...

01 May 2023 1,386 0 View

Can you make changes to Supplementary Data during the post-acceptance proofing stage?

When I receive a proof for a manuscript, it is always for the main text. But do journals also allow changes to made to the Supplementary Tables/Figures if there are some typos?

01 May 2023 1,142 2 View

Why do journals allow authors to be reviewed by close associates?

I have come across several articles published by leading journals where the reviewer of the article (named) is actually one of the close associates of the authors. Some reviewers have their work...

23 April 2023 8,563 4 View

Is the seed of a miRNA functionally separate to the rest of the sequence?

The 7 nucleotide seed is the target for binding to the right mRNA to silence its transcription. Is this mini-sequence functionally separate to the remaining 15 or so nucleotides or does it...

07 October 2016 1,620 0 View

To what extent can gene duplication explain the evolutionary origins of new types of genes?

It is estimated that 80-90% of the genes in a typical eukaryotic genome are duplicates of more ancient genes. Many of these copies have diverged in sequence over time but few, if any, have become...

12 October 2013 6,064 27 View

How do Transcription factors find their recognition sites on chromosomes?

Once assembled in the ribosome, how (and why) do transcription factors proceed to traverse the DNA molecule to find sites that they can bind to? It has been proposed that they "slide down" the...

08 October 2013 4,042 10 View