Can I use whole-cell patch clamp to measure AMPA-mediated mEPSC in purkinje cells between P10 and P15 considering space clamp problems?

I'm trying to find a method to study the number of active mature synapses of purkinje cells (PCs) in the critical week of cerebellum development. I thought about mesuring AMPA-mediated mEPSC...

02 October 2017 511 1 View