Question about Patch-clamp.I have signals of EPSC which is more than 50 pA when clamping at 0 to record sIPSC. What should I do?

I am recording sEPSC(holding at -70 mV) and sIPSC(holding at 0) these days. My internal solution is Cs-based low Cl solution. But EPSC still appears when I was recording sIPSC which is obviously...

06 June 2022 9,008 3 View