Jérôme Dormoi

5 Questions 9 Answers 0 Followers

Questions related from Jérôme Dormoi

What is the best method to check interaction between a drug and a protein ?

Hi, I would like to know the best method to check the interaction between a proteine (cruzipain, cysteine protease) and a drug. It has been purposed to our project to evaluate protein-drug...

31 October 2020 7,319 3 View

Is It possible to design Affinity Chromatography Column with the Drug of your choice ?

Dear, I am interesting in Drug /cellular partner interaction analyzed by High Performance Affinity Chromatography (HPAC). I ask The question and I open a topic to know if It is possible to...

14 October 2020 7,609 3 View

How to generate viable free extra-erythrocytic forms of Plasmodium falciparum ?

Hi everybody. My question today is about generating free malaria parasite. I would like to know if someone is able to give me a protocol to extract this parasite from RBC, using saponine ? using...

02 July 2018 145 11 View

What is the maximum dose of ethanol and tween20 which can be administered to BALB/C mice (7 weeks old)?

I try to solubilize a powder with a mixed solution of tween20 and ethanol for only two injection (IP) in 7 weeks old BALB/c mice. The injection volume is 100µL. Can you help me ? Regards and Thanks

10 April 2015 3,547 4 View

Are High Performance Affinity chromatography or others Chromatography tech. a tool to identify drug/ cellular partner by fixing drug on the Column ?

Dear, I would like to know if some researchers have already experienced HPAC or others chromatography methods to identify UNKNOWN cellular partner in drug interaction. This topic can help me to...

01 January 1970 6,728 2 View