Jane Doe

2 Questions 2 Answers 0 Followers

Questions related from Jane Doe

Are the C3, C4 and C6 positions of the hydroxyl groups on mannose adequately exposed to solution if using DSPE-Mannose in nanoparticle incorporation?

I am using ConA to validate a post-insertion approach to get a ligand linked micelle incorporated into LNPs - ConA should bind specifically and with high affinity to mannose, but I am not seeing...

08 August 2022 5,947 0 View

Micelle size for DSPE-PEG2k should be between 20-30nm, but on DLS I am seeing very large complexes/aggregates. Why is this so?

I am using a lipid film technique where the lipids are dissolved in chloroform, dried into a lipid film and then rehydrated in tris buffer. The micelles are giving me three populations on the DLS,...

01 January 1970 5,383 5 View