Does anyone have experience with large pressure fluctuations in NP-HPLC using dried solvents?

I'm usiing an Agilent 1100 series for NP purposes, using a quaternary pump. I have used it for a long time with n-heptane and dichloromethane as solvents in isocratic runs, using standard seals...

21 October 2019 2,188 4 View