Harshad Paithankar

14 Questions 6 Answers 0 Followers

Questions related from Harshad Paithankar

Is it possible to have high R2 effective rates in CPMG relaxation dispersion experiments than those obtained by nuclear spin relaxation experiment?

I am analyzing some CPMG relaxation dispersion data. The effective rates of relaxation R2eff I am getting by fitting intensity values in all the models are higher than the R2 values I am getting...

11 February 2017 1,056 1 View

I want to know about Mass spectrometry based dynamic studies of proteins. Can any one help?

I am reading some articles about use of ion mobility-mass spectrometry for determination of dynamics of proteins. I am not able to understand how to convert mass data to the structure of any state...

15 September 2015 3,547 3 View

Which proteins can be separated by using reverse phase HPLC?

Is there any comparative study of protein purification or separation by using reverse phase HPLC and fast protein liquid chromatography (FPLC)? What are the criteria for separation of protein by...

29 March 2014 6,756 1 View

Does anyone know any HPLC methods having a mobile phase with the combination methanol/water or acn/water?

I want to study these methods for a project. Please also give retention time and retention factor for as many drugs as available.

26 July 2013 9,042 3 View

is there any reference where I can get UV spectra for the various molecule?

I am interested for the UV spectra of vitamins.

02 March 2013 1,649 3 View

How to increase dissolution of fexofenidine in dissolution medium?

The release need to be tested for sustained release tablets.

24 February 2013 8,538 1 View

How can we distinguish between different types of columns?

for example, ODS, synchronus, hypersil, nucleosil, etc.

06 January 2013 4,639 9 View

Can any one give me information about computer aided drug design?

I want to study properties of the molecules designed. i want to know about polarity of the molecule and its pKa. can it be predicted from CADD?

27 December 2012 6,440 8 View

Can anyone share information about the scanning speed of the UV detector and PDA detector of HPLC systems?

Is there any variable in UV detectors, which give equal or better scanning speed than PDA detectors? What is the scanning speed of the different systems?

23 November 2012 4,434 4 View

How can we define method validation?

How to validate an analytical method?

13 October 2012 2,300 5 View

Is there any method for HPLC analysis of Dicyclomine hydrochloride? Is it possible to analyse this drug by spectrophotometry?

This drug is bi cyclic molecule without any unsaturation on the structure.

12 September 2012 2,928 2 View

Is there any spectroscopic method for analysis of antiretroviral drugs?

Mainly lopinavir and ritonavir

24 July 2012 3,400 3 View

Does the detection frequency of HPLC-UV detector affect the peak area? If yes is it better to set the frequency low or high for low noise?

I am using jasco hplc with uv detector and borwin software.

29 April 2012 2,529 4 View

Can anyone help me to understand various HPLC software? Which softwares are more commonly used for the method development purpose?

Is it possible to get various softwares or at least their user manuals to understand them? Is it possible to download such information from anywhere?

28 March 2012 4,516 14 View