Gaurav Bedse

4 Questions 9 Answers 0 Followers

Questions related from Gaurav Bedse

Can I divide a treatment group as responders and non-responders ?

I have treated ICR mice with an anxiolytic drug. I observed that almost 60% mice are responding to treatment (means giving anxiolytic effect) and 40% aren't (same as that of control group). Can I...

18 February 2016 5,537 8 View

Can anyone suggest a probe sonicator to homogenize mouse whole brain?

I am looking for a good sonicator to homogenize mouse whole brain. The homogenizer should not produce heat. We are going to analyze brain lipids by mass spectrometry.

28 July 2015 647 4 View

How to freeze brains after perfusion to cut them on cryostat?

Hi Everybody, I am new to immunohistochemistry and immunofluorescence techniques. I need a protocol for freezing brains after paraformaldehye perfusion. I want to cut brains on cryostat. I want to...

31 July 2014 5,171 12 View

Does anybody know Thioflavin-S Staining method for amyloid beta quantification? Is it well accepted method?

I am interested to study effect of a treatment on amyloid beta plaques deposition in transgenic mouse model of AD. Can I use Thioflavin-S Staining method for amyloid beta plaque quantification?

09 July 2014 6,911 6 View