What's the effective dose of tamoxifen to induce the recombination of CreERT2 x R26EYFP in mouse embryonic liver during gestation?

We have experienced significant difficulty when inducing the recombination of a CreERT2 Tg mouse line in fetal liver for lineage tracing purpose. CreERT2 mice were mated with R26R-EYFP report...

07 January 2015 9,519 3 View