Dinhvu Nguyen

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How to activate 5,5,6,6,6-Pentafluorohexan-1-ol ?

I need to make an esterification between 5,5,6,6,6-Pentafluorohexan-1-ol and any simple primary carboxylic acid.(coupling agent such as EDCI/DMAP, HOBt or activation by making an acyl chloride) It...

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How can one avoid the oxidation of a metal carbenoid ?

I tried to prepare a functionalized gamma butyrolactone by C-H insertion mediated by a metal carbenoid. However a variety of metal (Rh, Pd, Ag, Cu) cleanly lead to the formation of the...

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