Derek J Langeslay

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Questions related from Derek J Langeslay

RCE-SDS of mAb: What is the peak migrating in between HC and HC-LC thioether?

I've been looking through literature of reduced CE-SDS of monoclonal antibodies and I frequently see this 'post-HC' peak. I don't know if it is specific to a particular IgG, but I see it...

17 March 2021 4,356 0 View

Does anyone calibrate the mass of their Sciex TripleTof above 922 Da? If so, what calibrant do you use?

I would like to calibrate my 5600 TripleTof in the 1500 Da to 3000 Da range for some intact protein LC-MS experiments, but he Sciex standards max out at 922 Da (APCI positive calibrant). Does...

25 May 2017 7,725 2 View