Charles R Robertson

3 Questions 26 Answers 0 Followers

Questions related from Charles R Robertson

I recently oxidized a 15 kDa dextran to the dex-aldehyde. Zeta potentials showed increased negative charge. What is the reason for this?

I began with 15 kDa dextran (-3 mV average zeta), and hit it with oxidant to produce an 80% dialdehyde content dex-aldehyde with a zeta of -7.5 mV. After dialysis, I conjugated an amine compound...

06 November 2013 928 1 View

How do you remove salts from water soluble organic compounds?

I have a cytidine•HCl analog, and would like to do some chemistry on it, but the HCl is limiting my solubility in organic solvents. I would like to remove the HCl, but the kicker is the...

19 June 2013 6,660 88 View

Selection of an ion exchange resin for the separation of nucleotides from nucleosides - can anyone help?

I am working on the phosphorylation of cytidine analogs and would like a robust way to separate the nucleoside from the nucleotides. I plan on working on the gram scale, so an anionic exchange...

29 May 2013 2,033 1 View