Barry James Barclay

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Questions related from Barry James Barclay

How is it possible to have aneuploid tumor cells with numerous chromosome rearrangements and 2n lineages within the same tumor?

This is my explanation. In some cases it is result of thymidylate stress. This is a cdc21 (TYMS) mutant cell line of S. cerevisiae with thymidylate added to a center well establishing a radial...

01 January 1970 6,015 4 View

This a fascinating idea. I wonder if cancer stem cells that show numerous gross chromosomal rearrangements have transdifferentiation gene expression?

ie support the epigenetic model of carcinogenesis

01 January 1970 9,382 14 View