Ayman Jafar Oweida

4 Questions 5 Answers 0 Followers

Questions related from Ayman Jafar Oweida

How can you separate multi-nucleated and/or large cancer cells from their counterparts in the same dish in tissue culture?

Cancer cells often show heterogeneity. One aspect of heterogeneity is the presence of multi-nucleated and/or large cells in the general cell population. How can one separate this population while...

04 December 2014 1,169 3 View

Does anyone have experience with intra-thoracic tumor injections for an orthotopic lung tumor model?

Previous reports have shown the feasibility of generating an orthotopic primary lung tumor model in rats using an intra-thoracic injection of cells in matrigel. Reference for the rat model can...

16 February 2014 9,671 4 View

Why do some cancer cells become more invasive after being treated with high doses of ionizing radiation?

Numerous papers have reported increased invasion of cancer cells after treatment with high doses of ionizing radiation. I have seen this in my work with lung cancer cells as well. Is there a...

26 September 2013 8,058 3 View

Why do cells with EGFR activating mutations respond to tyrosine kinase inhibitors (eg. gefitinib/erlotinib)?

Particularly in non-small cell lung cancer, there's a population of patients who carry mutations in the epidermal growth factor receptor gene. These patients are much more likely to respond...

17 September 2013 6,077 3 View