Atul Udgata

2 Questions 12 Answers 0 Followers

Questions related from Atul Udgata

PH of ATP for NLRP3 inflammasome activation?

A solution of ATP is mildly acidic in nature. As acidic pH is known to have a stimulatory role in inflammaosme activation, i was wondering if one has to maintain the pH at 7 or just leave it as it is?

23 November 2016 9,030 6 View

Is it possible to introduce a knock-in of a gene in THP-1 cells by CRISPR/Cas9 method by HDR? If not, then is there any other way to do it?

I need to study point mutations in a gene in order to understand its function in response to certain stimuli. So, i want to create a knock-in of the mutated gene by CRISPR/Cas9 via...

12 October 2016 2,285 6 View