Ashraf H. Abadi

4 Questions 8 Answers 0 Followers

Questions related from Ashraf H. Abadi

HTRF PD1/PD-L1 assay?

Hi everyone I am looking forward to a potential collaborator/company who can perform HTRF assay to test the potential PD1/PD-L1 inhibitory effect for 40 small organic molecules. For a company I...

19 February 2022 9,290 0 View

Correlation between binding and functional activity?

Is there a clear correlation/no correlation between having a strong binding to a receptor and having a functional activity (agonism/antagonism) on it? and Vice versa? particularly for GPCR. In...

25 March 2017 7,255 2 View

I need the detailed experimental protocol for the preparation of the mice/human S9 fraction and its use in a metabolic study of a xenobiotic?

How to extract and prepare the S9 fraction. Its storage and use to study the metabolic stability and metabolites for a xenobiotic. DETAILED EXPERIMENTAL PROTOCOL

15 July 2016 1,374 3 View

Can inhibitors with different binding modes to an enzyme have different consequences on biology outcome?

If the binding mode of inhibitors to an enzyme is differed may this alter the biological outcome?

21 November 2012 8,938 3 View