Is there an upregulation of some M2 markers while polarising macrophages to M1 and vice-versa?

When I try to polarize murine BMDMs to M1, Arg-1 is simultaneously upregulated with other M1 markers. On the other hand, in M2 polarization protocols, iNOS and IL-6 upregulation is seen. Has...

22 January 2015 6,265 7 View