Arehalli S Manjappa

4 Questions 4 Answers 0 Followers

Questions related from Arehalli S Manjappa

Do HepG2, Hepatocellular carcinoma (liver cancer), cell lines over express CYP3A4 enzymes ?

We want to know the liver cancer (HCC) cell lines or other cell lines which overexpress the CYP3A4 enzymes. Do HepG2 overexpress CYP3A4 ? Please share some published articles which confirms the...

01 January 2020 4,300 3 View

What justification can be given when the entrapment efficiency of nanoparticles is more than 100%?

Dear all, We have prepared micellar nanoparticles which showing entrapment efficiency of more than 100% (108%). I believe that it is probably due to overweight of drug taken and then the complete...

12 December 2019 3,265 5 View

We want to synthesis Cisplatin - Stearic acid complex (Simply a salt form). Can anybody suggest a simple scheme to prepare the said complex?

We want improve Cisplatin-loading in lipid based nanoparticles. Therefore, we believe that lipid (For instance, Stearic Acid) salt of Cisplatin perhaps improve the cisplatin loading in lipid based...

12 December 2017 5,956 2 View

Please suggest me the easiest reaction scheme to prepare Methotrexate and Alendronic acid sodium conjugate, either through ester or amide linkage?.

Can anyone please suggest me the easiest reaction scheme to prepare Methotrexate and Alendronic acid sodium conjugate, either through ester or amide linkage?. Please see the attachment for...

07 July 2017 4,402 4 View