Why ICV-STZ (3 mg/kg) is given twice (on day 1 and day 3) to establish a rat model of Alzheimer's disease?

Hi everyone, What is the rationale behind the administration of intracerebroventricular streptozotocin (ICV-STZ) in a dose of 3 mg/kg twice (day 1 and day 3) in rats to produce an animal model of...

26 July 2020 8,398 2 View