Ansab Akhtar

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Questions related from Ansab Akhtar

Why ICV-STZ (3 mg/kg) is given twice (on day 1 and day 3) to establish a rat model of Alzheimer's disease?

Hi everyone, What is the rationale behind the administration of intracerebroventricular streptozotocin (ICV-STZ) in a dose of 3 mg/kg twice (day 1 and day 3) in rats to produce an animal model of...

26 July 2020 8,492 2 View

Is it necessary to add a complex IV inhibitor in the determination of complex I in intact mitochondria by the method of 'King and Howard 1967'?

In Complex I assay with intact mitochondria, reduction of cytochrome c at 550 nm, is it important to use an inhibitor of complex IV like cyanide or azide in the assay to prevent the further...

18 July 2020 2,154 0 View

Is there any particular method to assess mitochondrial complex-III activity? What about MTT assay?

I would like to ask about a specific method for the determination of mitochondrial complex-III activity. There are reports of MTT assay as an indirect method for finding out mitochondrial...

28 June 2020 2,683 0 View