Is Western blotting a reliable and clinically validated means of detecting BCR-Abl fusion protein in chronic myeloid leukaemia?

In the absence of quantitative real-time PCR as a means of detecting the oncoprotein BCR-Abl, can one reliably use Western blotting (WB) in the diagnosis of CML? Since BCR-abl is a 210kDa protein...

02 November 2015 7,107 7 View