Alice Holly

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Questions related from Alice Holly

Is there any known functional consequence of the ESR1 alternative variants 2 and 3?

ESR1 mRNA variants code for 3 protein variants. The second contains an additional 2 AAs. Isoform 3 is lacking an amino acid at the N-terminus. Is there any known functional consequence of these...

08 October 2014 4,736 1 View

Is it possible to use produce a ESR1 shRNA cell line with MCF7s or T47D's without causing growth arrest? Has anyone done this?

Is it possible to use produce a ESR1 shRNA cell line with MCF7s or T47D's without causing growth arrest? Has anyone done this? I could not find a successful reference in the literature. Many Thanks

20 August 2014 385 2 View