Alagu Sankareswaran

3 Questions 4 Answers 0 Followers

Questions related from Alagu Sankareswaran

When to use inverse rank based normalization for phenotypes in genetic studies?

One of the assumptions in linear regression is that the data should be normally distributed. My data is skewed. I tried log, square root, and several other transformations which I could find still...

31 May 2021 2,353 7 View

How to identify covariates statistically for a genetic association studies?

The genetic association studies need to be adjusted for the covariates such as Age, Gender etc. Is there a statistical way to figure out that? And is it required that all these covariates should...

13 January 2021 451 3 View

How to get TOPMED reference panel ( or south asian specific) for the imputation in Michigan Imputation Server?

Hi All, I am staring into imputation of variants for the genome wide scanning array in past weeks. Though I am able to do imputation using 1000GP3 panel using Impute2 for my dataset, I...

22 August 2020 2,785 1 View