Ahmed H Abdelazeem

5 Questions 10 Answers 0 Followers

Questions related from Ahmed H Abdelazeem

Why do some chemists prefer to perform N-formylation for the free amine before coupling reactions rather than reacting the free amine directly?

Recently, I've seen in a patent a simple N-alkylation reaction of 2-aminobenzothiazole with ethyl bromoacetate. The inventors have carried out N-formylation reaction first followed by coupling...

26 March 2015 6,841 7 View

How can I prepare 1-adamantane carboxamide from 1-adamantane carboxylic acid or 1-adamantyl carbonyl chloride in the absence of ammonia gas?

I tried ammonium hydroxide solution on acid chloride but, it did not work. I do not have ammonia gas in our lab. Thanks

02 November 2014 9,016 6 View

What are the best reaction conditions for the conversion of thiol (SH) group on a heterocycle ring into hydrazide?

I've used excess hydrazine hydrate in ethanol with reflux for more than two days. The reaction is still incomplete and there is a lot of the starting thiol material. Any suggestions?

16 February 2014 3,764 11 View

Cyanogen bromide (BrCN) handling and safety?

It is the first time that I will use BrCN reagent to form a triazole-2-amino ring. I'm worried about its toxicity and dealing with it. Is there any experience or advice regarding this reagent?...

03 May 2013 6,745 6 View

How could I get any information about a compound if I have only its CAS Registry Number ?

I just need the reference title, volume, title, year and issue no where it was published.

01 April 2013 9,662 18 View