Ahmad Zidan

11 Questions 13 Answers 0 Followers

Questions related from Ahmad Zidan

When you have a protein as a start, What are the best bioinformatics tools to identify candidate ligands?

There are many tools to identify the protein target for a ligand. When I start with a protein, what are the best tools to figure out the possible chemical ligand for this protein?

10 August 2020 9,128 3 View

How can I calculate minimum effective conc. if I have dissociation constant ?

I have dissociation constant (Kd) for a drug- receptor complex. Can I calculate the minimum effective conc. (MEC) using this Kd? How also can I calculate the oral dose that will cause this MEC or Kd?

21 July 2018 856 3 View

How to detect the best variant affecting patient's response to a drug?

I detected a set of patients that have a high response to a drug. Each patient has 40 different reads ( 20 nominal and 20 continuous) resemble certain genetic and expression variations. How should...

24 April 2016 1,711 3 View

Is there a source where I can find the 3D structures of the different protein alleles?

I need 3d structures of different alleles of the same protein.

12 November 2014 3,681 2 View

Is there an in silico method to predict the action of a ligand on an enzyme?

Can I computationally predict whether my ligand is an activator or inhibitor to the enzyme?

23 May 2014 7,539 11 View

Is there software to predict Kd or Ki for ligand-protein complex ?

I need to computationally predict Kd constant for a drug-enzyme.

29 April 2014 7,617 2 View

What is meant by the odd ratio (OR) in pharmacogenomics?

What is meant by an odd ratio > 0.3 in a study?

20 April 2014 5,080 7 View

How often do de novo mutations occur in the human genome?

If the same human genome is sequenced after five years of its first sequencing, will it be different?

19 April 2014 830 6 View

What is the meaning of x- coverage in next generation sequencing? Is it different from % coverage?

A little bit confused about x- coverage and % coverage

07 April 2014 8,977 15 View

Can any one explain briefly different types of electromagnetic waves? Is light an EM wave?

I'm a little bit confused about the different types of EM waves.

02 April 2014 422 3 View

Is there a database for drug related gene expression information?

Database for microarray data after administration of a certain drug.

11 October 2013 5,631 1 View