This question applies to the use of nanotechnology (dispersion of nano-particles in a lubricant to form a colloidal mixture of nano-lubricant and refrigerant) in energy efficient air conditioning systems.
I am not sure whether nanoparticles-dispersed lubricant is being commercially used.
The main difficulty that hinders the nanoparticles to be used in refrigerators or air-conditioners is the stability of dispersion of nanoparticles in the refrigerant over the normal operating temperatures and the durability. Due to high surface area to volume ratio of nanoparticles, higher chance of agglomeration to form microsized particles lead to clogging to the surfaces through which they flow if precautions are not taken care of.
I though as the refrigeration systems have higher pressure, higher velocities, and higher tubes diameters, than that air conditioning units have; then the chance of particles settlement/agglomeration will be less and if it happens it will don't close system's tubes due to larger area.