I don't if I good understand the question but if yes, the answer is yes, this is possible to do image the biological materials. I suggest used low vacuum and low voltage.
With proper specimen preparation you can observe any specimen in any SEM mode (high-vac, low-vac, environmental). It all depends on your goals. If you need more information you need to supply more information about your task.
The ability of environmental scanning electron microscopy (ESEM) to image insulating and/or moist specimens without the need for the removal of volatile components or the application of a conductive coating has significantly increased the potential range of experiments and observations that can be performed at the high resolution of electron microscopy. Such a technological advance has particularly important implications for the study of biological systems, as well as other soft, moist materials and complex fluids. Native - state biological ultrastructures are demonstrated across a range of length scales, from whole organisms to tissues and cells
Dr D.J. Investigating Biological Ultrastructure using Environmental Scanning Electron Microscopy (ESEM), Stokes, Science, Technology and Education of Microscopy: an Overview 564, Polymers & Colloids Group, University of Cambridge, Dept of Physics, Cavendish Laboratory, Madingley Road, Cambridge, CB3 0HE, UK.