I came across articles reporting that chitosan will be released in large intestine (also it inhibits the fat digestion). But researchers produced the O/W emulsion (fish oil, beta carotene) with chitosan as stabilizer.
Will the material (betacarotene) be released in the small intestinal stage for absorption?
Hi Joseph
Chitosan is a charged Polyaminosaccharid, it has physical properties much different than beta-Carotene, so there is not much risk that you block you absorbtion with it, Carotene has no Acid-Group and no charging that would inable an absorption on the Chitosan surface. The way of reducing fats in case of chitosan is the absorbing of free fatty acids after digestion with Lipases. The carotene itself has more affinity to lipidic environments like the fish oil, so if you can release it from there, Chitosan should not be a problem....
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