As a general rule, the absent tooth will be the most distal tooth of any given tooth type . Lower premolars are the most frequently absent teeth with a prevalence of
2.6% (mainly symmetrical) followed by missing upper lateral incisors at 2% (more frequently bilateral than unilateral). The treatment options for missing upper lateral
incisors usually include space closure with canine substitution or space opening with subsequent restorative replacement. Only on rare occasions are patients either happy to accept the aesthetics of the missing lateral incisor, or is the space ideal for a direct prosthetic tooth or canine build up.So, When are Space Opening and Space Closure Appropriate?