I prepared ligand forcefields with CGenFF server according to the method described by http://www.mdtutorials.com/gmx/complex/02_topology.html . But my ligand penalty values are (param penalty= 81.000 ; charge penalty= 57.072). What can I do to make these penalty values less than 50. Can I get reliable results if I use the ligand as it is for Molecular Dynamic simulation with GROMACS?