من اخطر الامراض التي تصيب الانسان ونسبة اصابه النساء اكثر من الرجال ويوداد خطوره كلما تقدم الانسان بالعمر
قد تؤدي الإصابة بمرض هشاشة العظام، في الغالب، إلى كسور في العظام، معظمها في عظام العمود الفقري، الحوض، الفخذين أو مفصل كف اليد. وبالرغم من الاعتقاد السائد بأن هذا المرض يصيب في الغالب السيدات، إلا أن هشاشة العظام قد تصيب الرجال أيضاً. وبالإضافة إلى المصابين بمرض هشاشة العظام، هنالك الكثيرون أيضاً ممن يعانون من هبوط كثافة العظام.
- Female gender, Caucasian or Asian race, thin and small body frames, and a family history of osteoporosis. ...
- Cigarette smoking, excessive alcohol and caffeine consumption, lack of exercise, and a diet low in calcium.
- Poor nutrition and poor general health.
Very stimulating question with several valuable and informative replies .
- Female gender, Caucasian or Asian race, thin and small body frames, and a family history of osteoporosis. ...
- Cigarette smoking, excessive alcohol and caffeine consumption, lack of exercise, and a diet low in calcium.
- Poor nutrition and poor general health.
Hi.
These things increase the risk of osteoporosis
#1 - insufficient resistance (weight training / heavy lifting)
#2 - insufficient vitamin K2 and D in particular (but Mg, Fe, P, and Ca as well).
#3 - taking calcium supplements, especially if 1 and 2 above are the case.
Insufficient Resistance
The body conserves resources in response to what it thinks is going on. In nature, when our ancestors needed strength (for speed or particular tool use) the forces increased mechanical strain. This signals need for more strength. Very specific muscles (type II fibers for strength) and bones would naturally develop in response. For bones, the constant balance between osteoblasts (building) and osteoclasts (tearing down) was always at work to remodel, building up bone regions in greatest need of strength and sometimes taking away from areas never experiencing significant strain. Carrying a very heavy loaded basket or using a heavy axe for even just a few minutes per week -- if the strain was significant -- would be enough for this. In contrast, modern people who do not experience heavy strain will not develop stronger muscles and associated bones. Serious exercise can be very beneficial but without the serious strain aspect will generally not result in stronger muscles or bones. Older weaker people in particular are most in need of (supervised) weight training where stretching and warm up is followed by whatever amount will result in soreness over the next days, calibrated to the person. This might be holding maybe only 5lbs while squatting down and up just two or three times. This is the signal that adjusts osteoblast to osteoclast activity ratios to maintain strong bones. Anything skipping this step is ineffective by comparison.
Insufficient vitamin K2 and D (and other minerals)
Few people consume insufficient calcium. Most humans, however, produce (from the sun) or consume insufficient vitamin D, causing a great many problems, including calcium update and mobilization problems. Vitamin D is particularly high in sun dried mushrooms, salmon, cod liver oil and is fat soluble. (Swallowing a vitamin D pill without simultaneously eating an oily or fatty meal may be ineffective). Vitamin K2 -- also fat soluble -- is naturally high in natto and aged cheese. It modulates osteoblast/osteoclast balance in favor of osteoblast activity by impacting the release of enzymes processing Ca. Magnesium (high in cocoa, pumpkin seeds, spinach, lima beans, tuna) as a +2 cation is physiologically balanced with Ca +2 in the body. Insufficient magnesium makes it harder for the body to keep calcium levels optimal.
Taking calcium supplements, especially if 1 and 2 above are the case.
If the above two are even partially in effect, calcium supplements may accumulate in the blood where they might contribute to calcification of the arteries. Unlike food delivery, supplement delivery can potentially result in very high concentrations (kind of like how refined sugar can result in a high blood sugar spike compared to similar carb quantity in a raw sweet potato). This calcium spike can trigger calcium receptors to down-regulate, making the body less sensitive to calcium. Also, this might trigger an adaptive response which will lower blood pH. This more acid blood will leach calcium from the bones. Most importantly, if the previous conditions are not met -- especially the first -- the body will have no need for calcium in the first place, no ability to productively use additional calcium, or both. An analogy might be a home where a goal is to remodel the kitchen. If the cook of the family doesn't share this goal, bashing down the front door with a box of hammers won't help.
Hope that helps!
It depends on many factors including age, sex, hormonal status, general nutrition, and bit. D deficiency between others...
Osteoporosis leads the bone to deterioration of its microarchitecture due to bone density loss, enhance bone fragility and increases bone fracture risk.
Factors that make osteoporosis more likely include:
Age. Your bone density peaks around age 30. After that, you’ll begin to lose bone mass. So that’s all the more reason to do strength training and weight-bearing exercise -- and make sure you get enough calcium and vitamin D from your diet -- to keep your bones as strong as possible as you get older.
Gender. Women over the age of 50 are the most likely people to develop osteoporosis. The condition is 4 times as likely in women than men. Women's lighter, thinner bones and longer life spans are part of the reason they have a higher risk. Men can get osteoporosis, too -- it’s just less common.
Family history. If your parents or grandparents have had any signs of osteoporosis, such as a fractured hip after a minor fall, you may be more likely to get it, too.
Bone structure and body weight. Petite and thin women have a greater chance of developing osteoporosis. One reason is that they have less bone to lose than women with more body weight and larger frames. Similarly, small-boned, thin men are at greater risk than men with larger frames and more bodyweight.
Certain diseases. Some diseases such as rheumatoid arthritis raise the odds that you’ll get osteoporosis.
Some medications. Certain prescription medications -- for example, if you take steroids such as prednisone for a long time -- can also boost your odds of getting osteoporosis.
Smoking. It’s bad for your bones. To lower your risk of osteoporosis and fractures -- and many other health problems -- work with your doctor to kick this habit ASAP.
Alcohol. Heavy drinking can lead to thinning of the bones and make fractures more likely.
https://www.webmd.com/osteoporosis/guide/osteoporosis-risk-factors
Bone tissue are dynamic entities. That is it has innate propensity to dynamic remodeling. But after 30 years of age, especially so in the females the osteoclastic activities supercedes the osteoblastic activities due to changes in various hormonal milieu of our body, that what leads to osteoporosis. Certain drugs, diseases and addiction adds fuel to this phenomenon further.
@Sumanta. Sumanta Chakraborty Kudos re blast/clast dynamics I emphasized above. It actually connects with observations to speak of "bone cell stretch receptors" (think weight training) involved with Ca-mediated signaling of AMPK/mTOR/etc as upstream regulators of blast/clast balance.
Please go through the following RG link.
Article A comprehensive overview on osteoporosis and its risk factors
- Female gender, Caucasian or Asian race, thin and small body frames, and a family history of osteoporosis.
- Cigarette smoking, excessive alcohol and caffeine consumption, lack of exercise, and a diet low in calcium.
- Poor nutrition and poor general health.
Osteoporosis Risk Factors - MedicineNet
www.medicinenet.com › script › main › article
One of the main factors is related to age because is a very clear relationship with older age. Also, another factor is gender because is much prominent in postmenopausal women
Prof Dr Suhad Qasim saeed Almousawi
https://www.bones.nih.gov/health-info/bone/osteoporosis/overview
Osteoporosis is a disease whose main consequence is bone fragility fracture. The risk of fracture associated with osteoporosis will depend on a series of factors that have a summative effect. The most widely used tool at the moment is FRAX, which is free to access and reports the absolute risk of fracture in the following 10 years.
https://www.sheffield.ac.uk/FRAX/index.aspx?lang=sp
The dominant factor leading to bone loss in older adults appears to be gonadal sex steroid deficiency, with multiple genetic and biochemical factors, such as vitamin D deficiency or hyperparathyroidism, that may accelerate bone loss. Current osteoporosis therapies mitigate or reverse the loss of bone associated with age-related decreases of gonadal sex steroids, increase bone strength, and reduce fracture risk.
Please have a look at the link below:
Article Osteoporosis: A Review
Osteoporosis is a systemic disease characterized by a decrease in bone mass per unit volume, compromised bone strength, which predisposes the affected bone to fracture. This is one of the leading causes of morbidity and mortality among the elderly over the world.
Please follow the link for a good insight:
Article Osteoporosis - An Update
Osteoporosis is a syndrome characterized by a significant decrease of bone mass and subsequent qualitative defects resulted to a decrease to bone strength and the appearance of unexpected bone fragility.
Osteoporosis is a major public health threat which afflicts 1 in 3 women and 1 in 12 men over the age of 50 worldwide.
It is responsible for millions of fractures annually, mostly involving the lumbar vertebrae, hip and wrist.
The risk of osteoporosis increase with the age, malnutrition, intestinal malabsorption, menopause and may other factors
Very good question with very relevant replies, osteophorosis may happen because lack of calcium, increases risk of bone fractures and result in weaken bones
The hip fracture and his consecuences is the most important consecuence of the osteoporotic bone
Osteoporosis is increasing in frequency in recent years all over the world
please take a look at this link:
Article Survey of Osteoporosis Risk Factors (Review Article)
Article Risk factors for osteoporosis: A review
Article A comprehensive overview on osteoporosis and its risk factors
Article The Prevalence and Risk Factors for Osteoporosis among 18 to...
Article Risk Factors for Osteoporosis and Fractures in Postmenopausa...
Article Osteoporosis: A Review
https://www.webmd.com/osteoporosis/guide/osteoporosis-risk-factors.
There are many excellent reviews and references about this clinical situation in the medical literature
Osteoporosis is a clinical condition which is characterized by bone microarchitecture disorder and high risk of fracture. As a result, this may affect people's daily life and of course their activities. That's why screening for osteoporosis in specific groups of people is essential.
The risk is different in relationship to gender, age, associated diseases and other ambiental factors also
Osteoporosis can be the cause of heart failure for a vulnerable population.
Unfortunately Osteoporosis is a “silent” bone disease because you typically do not have symptoms, and you may not even know you have the disease until you break a bone.
Is variable and increase over the time all the life and is greater in women, oin general
Dear Djeneba I would like you to explain to me which one I saw so that osteoporosis causes heart problems
Dear Edgar, thanks for your question. Kindly consult the following links that justify my response: https://www.sciencedaily.com/releases/2015/06/150629075938.htm
&
https://www.sciencedaily.com/releases/2015/06/150629075938.htm
Djenena Thank you very much for such valuable information that I was completely unaware of.
Prof Dr Suhad Qasim saeed Almousawi depends on gender age and yes will be mostly affected by the bones
It seemed that I would not be affected by this disease. But it took a year with cytostatics for osteoporosis to develop in the bones of one of the wrists.
Estimated Miroslaw , it is necessary to better determine that loss of bone mass in your wrist, since osteoporosis is a systemic disease, in your case the cytostatic is not the origin of this local problem. Sincerely
Risk factors for osteoporosis
inadequate amounts of dietary calcium.
low vitamin D levels.
cigarette smoking.
alcohol intake of more than two standard drinks per day.
caffeine intake of more than three cups of coffee or equivalent per day.
lack of physical activity.
early menopause (before the age of 45) https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/osteoporosis
What are the risk factors for osteoporosis?
Advanced age (≥50 years)
Female sex.
White or Asian ethnicity.
Genetic factors, such as a family history of osteoporosis.
Thin build or small stature (eg, bodyweight less than 127 lb [57.6 kg])
Amenorrhea.
Late menarche.
Early menopause.
https://www.medscape.com/answers/330598-82982/what-are-the-risk-factors-for-osteoporosis
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to bone fragility, and consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. After the broken bone heals, the person may have chronic pain and a decreased ability to carry out normal activities. https://en.m.wikipedia.org/wiki/Osteoporosis
Chinaza,You are a doctor from what country?, you use Wikipedia¡¡¡¡ to give information, excuse me but I think you are not reading science
Hello Madam, kindly look at this paper.
Article Osteoporosis: A social problem in the elderly population
The risk of getting osteoporosis increases with age as bones naturally become thinner. After age 30, the rate at which your bone tissue dissolves and is absorbed by the body slowly increases, while the rate of bone building decreases. So overall you lose a small amount of bone each year after age 30.
https://www.uofmhealth.org/health-library/te7603#:~:text=The%20risk%20of%20getting%20osteoporosis,each%20year%20after%20age%2030.
The risk of osteoporosis is running paralel to the age and of course is higher in older people
Many women replace osteoporosis with arthritis and believe they must wait for symptoms such as swollen and painful joints before visiting a doctor. We must emphasize that the mechanisms that cause arthritis are completely different from those that cause osteoporosis, which usually progresses quite a bit before the first symptoms appear. Osteoporosis often occurs very dramatically - a fracture of the spine, hip, forearm or any bone. These fractures often occur after seemingly minor traumas. In the late stages of the disease, pain, disfigurement, and weakness are common. After a large loss of calcium, the vertebrae begin to collapse and gradually lead to a hunched posture called kyphosis, or plain tongue “hump”. Although it is usually painless, patients lose up to 15 cm in height.
IOt must be calculated individually following an easy applicable formula
Uncontrollable risk factors:
- Sex: Osteoporosis is more common in women than men.
- Age: The older you are, the greater your chance of having osteoporosis.
- Race: Caucasians and Asians are more likely to have osteoporosis.
- Genetics: Your risk of osteoporosis is higher if it runs in your family.
- Menopause: This period in a woman’s life causes physical and hormonal effects. For example, it lowers your estrogen. These changes can increase your risk of osteoporosis. Your risk is even higher if you have early menopause (before age 45).
- Body frame: People who have small, thin frames are more likely to develop osteoporosis.
- Health: Certain conditions, such as cancer or stroke, can lead to osteoporosis.
Controllable risk factors:
- Lack of calcium and/or vitamins.
- Inactive lifestyle or lack of exercise.
- Smoking or tobacco use.
- Alcohol abuse.
- Eating disorders, such as anorexia nervosa.
- Hormonal imbalances. Examples include low estrogen or testosterone and high thyroid levels.
- Long-term use of certain medicines. Examples include corticosteroids and proton pump inhibitors (PPIs). Corticosteroids treat inflammation, pain, and chronic conditions, such as asthma and rheumatoid arthritis. PPIs help reduce stomach acid. These medicines can make it hard for your body to absorb calcium and cause osteoporosis.
Osteoporosis is a very common disease and the associated causes are varied. Between then we recall the post-,menopausal state mainly in women, the long-term treatment wit steroids, the obesity and so on...
Osteoporosis is more likely to occur in people who have: Low calcium intake. A lifelong lack of calcium plays a role in the development of osteoporosis. Low calcium intake contributes to diminished bone density, early bone loss and an increased risk of fractures. Eating disorders.
https://www.google.com/search?q=What+is+the+risk+of+osteoporosis%3F&rlz=1C1RXQR_enUS939US939&oq=What+is+the+risk+of+osteoporosis%3F&aqs=chrome..69i57j0i22i30l6j69i60.426j0j4&sourceid=chrome&ie=UTF-8
Excuse me but it is much more than a low calcium intake, many other factors are involved, such as hormonal and at the cellular level, especially with osteocytes.
There are many risks, the most prominent of which is bone fracture.
People who spend a lot of time sitting have a higher risk of osteoporosis than do those who are more active. Any weight-bearing exercise and activities that promote balance and good posture are beneficial for your bones, but walking, running, jumping, dancing and weightlifting seem particularly helpful.
-------------------------------
Exercise can help you build strong bones and slow bone loss. Exercise will benefit your bones no matter when you start, but you'll gain the most benefits if you start exercising regularly when you're young and continue to exercise throughout your life.
Combine strength training exercises with weight-bearing and balance exercises. Strength training helps strengthen muscles and bones in your arms and upper spine.
(citation from: Mayo Clinic, Osteoporosis).
Hi Prof Dr Suhad Qasim saeed Almousawi . I think it is more likely to occur in people who have: Low calcium intake. A lifelong lack of calcium plays a role in the development of osteoporosis. Low calcium intake contributes to diminished bone density, early bone loss and an increased risk of fractures. Eating disorders.See the link: https://www.mayoclinic.org/diseases-conditions/osteoporosis/symptoms-causes/syc-20351968
Osteoporosis is more likely to occur in people who have a sedentary lifestyle, low calcium intake, and other factors.
People who have a sedentary lifestyle have a higher risk of osteoporosis than those who are more active. Precise movements as part of the exercise can help and make our bones strong. Any weight-bearing exercise and activities that promote the health of the human movement system, especially balance and good posture, are beneficial for our bones. Walking, running, jumping, dancing, and weightlifting are excellent examples that seem helpful. Strength training helps strengthen muscles and bones in our upper limb and upper trunk as well.
Besides, A lifelong lack of calcium plays a role in the development of osteoporosis. Low calcium intake contributes to diminished bone density, early bone loss, and an increased risk of fractures. Moreover, Vitamin D deficiency can be a reason because Vitamin D helps the body absorb calcium. When vitamin D is lacking, the body cannot absorb adequate amounts of calcium to prevent osteoporosis.
Osteoporosis Risk Factors
https://www.uofmhealth.org/health-library/te7603
The risk of osteoporosis depends of one or several different associated factors and must be evaluated individually
Yeliz Kahraman :Very interesting what you said, please where you read this, Edgar Nieto MD
Excuse me but osteoporosis only affects the bone, the loss of muscle mass (sarcopenia) is related to age, it can facilitate the fall and the fracture
Depends of several factors that can be calculated in individual manner
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