What is the difference between protease and proteinase ?

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Chandan Thapa

protease are enzyme that degrade proteins by hydrolysis of the peptide bond . but some of the proteolytic enzymes act best on intact protein. proteinase are the protease that show specificity for the intact protein.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1147080/?page=1

Prasad Patil

Thanks Chandana Thapa sir......!

Sharmin Shahid Labony

protease is an enzyme that helps proteolysis

Ozkan Gelincik

https://www.qiagen.com/cn/resources/faq?id=64c67eac-3938-4fa0-8910-4e29e4d0f8f9&lang=en

QIAGEN Proteinase K is a subtilisin-type protease, which cleaves at the carboxyl side of hydrophobic, aliphatic and aromatic amino acids. It is particularly suitable for short digestion times. It possesses a high specific activity over a wide range of temperatures and pH values with substantially increased activity at higher temperature. Soluble calcium is not essential for enzymatic activity. This means that EDTA, which is used to inhibit Mg2+-dependent enzymes such as nucleases, will not inhibit Proteinase K activity. QIAGEN Protease is a broad-specificity Serine protease with high activity, cleaving preferentially at neutral and acidic residues. It is an economical alternative to Proteinase K for isolation of native DNA and RNA from a variety of samples.