Dear Karthick,

The chemical energy released in the formation of non-covalent interactions is typically on the order of 1-5 kcal/mol where these interactions can be resulted from  electrostatic, π-effects, van der Waals forces, and hydrophobic effects.

Anslyn, Eric (2004). Modern Physical Organic Chemistry. Sausalito, CA: University Science. ISBN 978-1-891389-31-3.

Noncovalent bonds – Molecular Cell Biology (textbook), Lodish, Berk, Zipursky, Matsudaira, Baltimore, Darnell.

Noncovalent bonding in Supramolecular Chemistry - Christoph A. Schalley

The following links containing recent publications on this topic:

http://link.springer.com/article/10.1134/S0022476615060360?no-access=true

https://www.researchgate.net/publication/235786866_Delocalization_indices_for_non-covalent_interaction_Hydrogen_and_DiHydrogen_bond

http://www.sciencedirect.com/science/journal/2210271X/998

http://www.ncbi.nlm.nih.gov/pubmed/24444143

Hoping this will be helpful,

Rafik

Article Delocalization indices for non-covalent interaction: Hydroge...

Rafik: What does "[t]he chemical energy released" mean?

Dear Martin,

This is the energy needed to break this kind of interactions.

Rafik