What are the mechanisms of drug-protein conjugate mediated adverse reactions? please with references.
Best regards
Here's a serious question: If we were to stop emitting all greenhouse gases right now, would the Earth's temperature start to cool down, or would the existing greenhouse gases continue to warm the...
30 July 2024 5,123 4 View
Dear colleagues i have synthesized CeO2 using green method and now the Np are not soluble in water how can I make it soluble in water? Best Regards
18 March 2024 4,496 2 View
Dear colleagues what are the biocompatible stabilizers that are soluble in PBS and can be used in anti cancer treatments?
15 March 2024 8,003 1 View
Hello dear teachers, I am currently conducting a research study for my master's degree, and I need your valuable contributions during this process. My survey is designed to explore factors that...
19 February 2024 1,138 0 View
How to determine the zero point charge for a schottky barrier or a composite consisting of more than one oxide for photocatalytic degradation ? Thanks
16 December 2023 478 6 View
Hello all, Hope this message finds you in good health. I am trying to analyze sensory data "9-hedonic scale" using RStudio, What is the best analysis to use, and is there a script I can...
18 November 2023 3,002 3 View
I have made positively charged nanoparticles with Lecithin, Squalene, Tween 80, Span 85 and Dotap. But after using ultrasonic, the particles are aggregated and their size increases. How can...
10 September 2023 3,280 3 View
I made cationic nanocarrier by lecithin, Squalen, tween 80, span 85 and DOTAP via melting method in 80 C, but nanoparticles had negative charge instead of positive charge. Does anyone know where...
04 August 2023 5,742 1 View
Hi, Can lipid nanoparticles larger than 200 nm pass through the 0.2 filter due to flexibility?
04 August 2023 2,727 2 View
Dear colleagues…. why we use the laser off time to calculate the photothermal conversion efficiency not the on time? Best Regards
25 June 2023 3,843 3 View
I am attempting to conjugate PEG to an amino acid at the C-terminus, for the purposes of producing nanoparticles. I have been told that PEG modified with amine groups can be used for this purpose,...
31 July 2024 2,033 1 View
It has been long known that EDC carbodiimide and NHS easter's half life agains hydrolysis are highly related to pH. However, very surprisingly, not yet found a paper giving a table/chart of their...
25 July 2024 8,738 0 View
For a partition of an integer \lambda, what does the difference \lambda_j - \lambda_{j+1} represent in relation to the conjugate partition, , with \lambda_j being the j-th element of \lambda?
23 July 2024 8,008 1 View
Hi everyone, I have conducted a mediation analysis with SEM. My model fit was good but there was no significant mediation. Which aspects of this should I discuss?
19 July 2024 4,272 5 View
So i have a few peptides (synthesized by SPPS and not cleaved from resin) and I want to add a maleimide label. We have NHS-PEG-Maleimide and from literature it is evident that the free amine group...
18 July 2024 4,075 3 View
I need Anti-Claudin8 Primary and Anti-Claudin2 conjugated Ab for my immunofluorescence experiment. If anybody has worked on it. Please share the accession number/details.
14 July 2024 485 0 View
Hello everyone, I am conducting a mediation analysis in JASP software. First, I checked for a general correlation with the IV-mediator correlation being significant at p =.015. Then, when I ran...
14 July 2024 3,458 1 View
I want to predict the DAR ratio based on the number of cys available for conjugation to Cys residue. I use Ellman's assay to predict the concentration of Cys after TCEP reduction. I gain a...
02 July 2024 612 6 View
Hello, I am doing some testing on lateral flow devices/materials and have run into a slight issue where I do not understand what the cause may be, but I have some ideas. General Experimental...
01 July 2024 7,960 3 View
Hello guys, I Have a question, I have structural equation model with multiple mediators, 2 mediator variables are dummy and 2 are continuous. I also heard that there is different manners of...
28 June 2024 6,186 1 View