What are the benefits we get in terms of stability, drug delivery, drug targeting, toxicity, biodegradability etc. (if I am missing something) by selecting one over the other?
Feel free to express your thoughts regarding this topic, even if they are not directly mentioned in any literature.
Carbon nanotubes are more cancerogenic, toxic and difficult to bio-degrade. Carbon nanotubes are also known for their poor absorption selectivity for chemicals. Cannot image using them for drug delivery..
Hi Oleg,
Actually researchers are trying to use carbon nano tubes for Targeted drug delivery specially in Cancer treatment.
Any comments on Polysiloxanes ?
Cheers!!
The basic white paper on polysiloxanes, including their drug delivery role, is
http://www.ijpras.com/pdfs/june_issue/Nusil_Silicone_Technology_in_Pharmaceutical_Drug_Delivery_System.pdf
The main advantage of polysiloxane is easy functionalization to fit a particular drug. Their derivatives can be linked through carbon-chain, ether bond or sulfur bridge. Carbon nanotubes can be functionalized as well, but less universally, because virtually all CN derivatives utilize ether bond.
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