I'm looking for different COVID-19 regimens that are being used for in-hospital patients.
Which are used for critical patients and which are for patients that are more mildly symptomatic?
When was the suggestion of each regimen by authorities?
WHO Guidance on Therapeutics in COVID-19 Nov 2020. https://apps.who.int/iris/rest/bitstreams/1316330/retrieve?fbclid=IwAR3pDNux6UR7qYXcT38I4T7p1whrbR0DvA-uT-pKrbMjUkDLCOOSUurCUQA
https://www.covid19treatmentguidelines.nih.gov/therapeutic-management/
In the earliest stages of infection, before the host has mounted an effective immune response, anti-SARS-CoV-2 antibody-based therapies may have their greatest likelihood of having an effect. In this regard, although there are insufficient data from clinical trials to recommend either for or against the use of any specific therapy in this setting, preliminary data suggests that outpatients may benefit from receiving anti-SARS-CoV-2 monoclonal antibodies early in the course of infection. The anti-SARS-CoV-2 monoclonal antibodies bamlanivimab and casirivimab plus imdevimab are available through Emergency Use Authorizations for outpatients who are at high risk for disease progression.
Remdesivir, an antiviral agent, is currently the only drug that is approved by the Food and Drug Administration for the treatment of COVID-19. It is recommended for use in hospitalized patients who require supplemental oxygen. However, it is not routinely recommended for patients who require mechanical ventilation due to the lack of data showing benefit at this advanced stage of the disease.
Dexamethasone, a corticosteroid, has been found to improve survival in hospitalized patients who require supplemental oxygen, with the greatest effect observed in patients who require mechanical ventilation. Therefore, the use of dexamethasone is strongly recommended in this setting.
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