I want to perform reductive amination of glycans using sodium cyanoborohydride as the reducing agent. Is there any advice on how to handle the reaction products, e.g. neutralise left over reducing agent before downstream purification methods?
Can you bring the pH low with HCl? This decomposes the sodium cyanoborohydride and generates hydrogen cyanide, so do this in a hood!.
Thanks for taking the time to answer my question.
Ok, yes that's something I could investigate.
Thanks again!
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