What are the best reagents to reduce aromatic nitrile (CN) to amine (CH2NH2) and de benzylation
2-(3-(benzyloxy)-2-methoxypyridin-4-yl)acetonitrile to 4-(2-aminoethyl)-2-methoxypyridin-3-ol
I am attempting to conjugate PEG to an amino acid at the C-terminus, for the purposes of producing nanoparticles. I have been told that PEG modified with amine groups can be used for this purpose,...
31 July 2024 2,033 1 View
I am new to research. The boiling point of triethyl amine (NEt3) is 89 degrees centigrade. I am skeptical that when I will let the hydrogen escape which is getting generated in situ, I will also...
21 July 2024 7,284 4 View
I examined telmisartan dissolved in methanol with a mobile phase of formic acid:acetonitrile (8:92) giving a retention time of 3.8. However, when I added acetonitrile to the solution the retention...
19 July 2024 5,462 2 View
I am searching for HPLC method to estimate Mirtazapine but i want to avoid HPLC-buffers as a mobile phase component. So, I am looking for alternative HPLC-solvent (acetonitrile, methanol etc.)...
14 July 2024 1,493 3 View
Hello guys. I have faced the problem of being in need of carboxyl-methylated amino acids. Amino acids I need are not available in the market so I need to synthesize them by myself. So thus I'm...
16 June 2024 9,920 3 View
How to stabilise the Schiff base product and avoid it from reverse back to the aldehyde and primary amine.
09 June 2024 9,264 5 View
Hi. i have a molecule it has both amide and ester bond. When i want to get second amide bond with ester part of the molecule by an amine, but it attacks to the amide bond also. In which conditions...
01 June 2024 9,863 2 View
Hello, in the research i'm working on,I have read many references that use a silver nitrat solution in acetonitrile with Tetebutylammoniumperchlorate . however, i have been unable to obtain this...
23 May 2024 4,373 0 View
I want to have amine group attached on the polystyrene particle surface. APTES can be used to do that.
21 May 2024 8,092 0 View
Free amine
26 April 2024 4,950 0 View