Scoring anxiety/depression/stress in clinical studies - acceptable tests?

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Natasha Campbell

Also the CSSR-S is typically required for any treatment that acts on the CNS and is widely used in clinical trials

Morten Hesse

If used as an outcome measure, there is actually some indication that the Clinical Global Impression scale is very sensitive to treatment effects. Probably the most evidence-based (and most expensive) thing is to combine multiple sources of information (BMC Psychiatry. 2011 May 14;11:83. doi: 10.1186/1471-244X-11-83.)