I wonder if anyone could tell me about the criteria of indexation of journals in Medline/Pubmed? Since the website shows several ways of getting indexed, e.g. submitting an application to Medline, submitting open access journals to pubmed central etc, what is the easiest way to get indexed? Why is it that so many applications of journals for indexation are rejected each year? And lastly, how is it that the Medline/Pubmed website states that a journal needs to submit its content for assessment during the application process of indexation while Biomedcentral journals are indexed even before they are launched? I hope someone can elaborate on these issues.