Are artificial immune system (AIS) algorithms considered as population-based? How about the newly developed chemical reaction optimization (CRO) algorithm? What are the similarities and differences between them? How do they differ from the robust and well-known Genetic Algorithm (GA), Particle Swarm Optimization (PSO), Ant Colony Optimization (ACO), Simulated Annealing (SA), Tabu Search (TS) and many more in terms of their behavior and operator characteristics?