In the first page of a newspaper I read about effectiveness of nasal spray to improve sociability and communication in children and teens with autism. Can you suggest research or other evidence supporting that this spay (oxytocin or other) is the treatment for autism ?
I also have found this article but I don't know if is it reliable http://www.autismspeaks.org/science/science-news/researchers-launch-study-oxytocin-nasal-spray
theres plenty of stuff showing its ability to enhance motivation to engage in social behaviour, but autism encompasses a vast range of deficits/abnormalities. oxytocin can't target them all, so its not "the" treatment. but it can point towards other related pathways e.g. dopamine signalling
At one time there was some research about oxytocin going on in Kansas, I thought. Maybe check with folks at University of Kansas?
National Public Radio broadcast a series on Oxytocin .
Scientists Intrigued By Test Of Hormone Spray For Autism, Scott Hensley February 10 2010
When the 'trust hormone is out of balance, Aliz Spiegel, April 22, 2012 (All things considered)
A life without fear, Alix Spiegel, April 26, 2010.
Also see the reference list from the article posted by Eric Hollander. There are many peer reviewed articles on the topic listed.
Here are citations for a few other studies (Google Scholar lists more than 4,000 titles since 2010:
Guastella, A. J., Einfeld, S. L., Gray, K. M., Rinehart, N. J., Tonge, B. J., Lambert, T. J., & Hickie, I. B. (2010). Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biological psychiatry, 67(7), 692-694.
Domes, G., Heinrichs, M., Kumbier, E., Grossmann, A., Hauenstein, K., & Herpertz, S. C. (2013). Effects of intranasal oxytocin on the neural basis of face processing in autism spectrum disorder. Biological psychiatry, 74(3), 164-171.
Anagnostou, E., Soorya, L., Chaplin, W., Bartz, J., Halpern, D., Wasserman, S., ... & Hollander, E. (2012). Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial. Mol Autism, 3(1), 16.
Anagnostou, Evdokia, et al. "Intranasal oxytocin in the treatment of autism spectrum disorders: A review of literature and early safety and efficacy data in youth." Brain research (2014).
Watanabe, Takamitsu, et al. "Mitigation of sociocommunicational deficits of autism through oxytocin-induced recovery of medial prefrontal activity: a randomized trial." JAMA psychiatry 71.2 (2014): 166-175.
Zoi, you should contact Associate Professor Adam Guastella. He is a Clinical Psychologist and Principle Research Fellow at the Brain & Mind Research Institute. (University of Sydney) Guastella was also one of the first to show that oxytocin enhances emotion understanding in young people with autism. Dr Guastella is currently evaluating whether oxytocin can be used to treat a range of mental health problems that are primarily associated with a difficulty in developing social-relationships.
Some of his studies are:
2013 A course of oxytocin to improve social communication in young children with autism; Guastella A, Whitehouse A, Gregory S; National Health and Medical Research Council (NHMRC)/Project Grants.
Neuroimaging oxytocin modulated plasticity, response markers and implication for treatment of Autism Spectrum Disorders and co-morbid intellectual disability; Guastella A, Johnston B; Endeavour Foundation/Research Support.
2012 Evaluation of a melanocortin agonist to improve social cognition in ASD; Guastella A, Hickie I, Young L; Simons Foundation/Research Support.
Investigating oxytocin to improve social difficulties in patients with autism; Guastella A; BUPA Foundation Limited (Australia)/Grants Program
Interesting study on this topic:
Elissar Andaria, Jean-René Duhamela, Tiziana Zallab, Evelyn Herbrechtb, Marion Leboyerb, and Angela Sirigua (2010). Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. PNAS 107 (9).
Kindly see the following RG links.
Article Intranasal oxytocin treatment for social deficits and biomar...
Article Effect of intranasal oxytocin on the core social symptoms of...
Article Long-Term Administration of Intranasal Oxytocin Is a Safe an...
Article Oxytocin: A Potential Novel Therapeutic Agent in Treatment of Autism
@ Zoi Amprazi
new study suggests that oxytocin nasal spray could be a solution, after researchers found it may work by improving self-control.
https://med.stanford.edu/news/all-news/2017/07/oxytocin-improves-social-abilities-
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