Per Invar Branemark stated as osseointegration the state of "functional" and "stuctural" connection between implant and bone . Technically he was referring to a mechanical bond both in micro and macro levels , since TiO2 is so stable it doesn't actually chemically connect with the proteins , cells and bone . However up-to-date coating materials offer a possibility of DIRECT CHEMICAL BONDING of the implant to the bone and that is indeed revolutionary . New construction techniques offer a strong bond between implant and bioactive substunces witch are actually integrated into the bone model .

Hope i could state my point , and that it is of your help

Kindly ,

Georgios A.

Osseointergation is basically a biologic bond

The ther osseointegration is qite broad as a term ! There are too complex interactions on a molecular and sub-molecular level at implant-tissue interface. I don't think that the therm "bond" is the most appropriate to describe those interactions .

Hello:

According to professor Brandmark in his article

Osseointegration in skeletal reconstruction and rehabilitation

Rickard Brandmark, MD, PhD; P-I Brandmark, MD, PhD; Björn Rydevik, MD, PhD; Robert R. Myers, PhD

J Rehabil Res DevVol. 38 No. 2, March/April 2001

He gives definition to osseointegration as follows

Definition of Osseointegration Osseointegration was originally defined as a direct structural and functional connection between ordered living bone and the surface of a load-carrying implant (4). It is now said that an implant is regarded as Osseo integrated when there is no progressive relative movement between the implant and the bone with which it has direct contact (2). In practice, this means that in osseointegration there is an anchorage mechanism whereby nonvital components can be reliably and predictably incorporated into living bone and that this anchorage can persist under all normal conditions of loading (5).

Now if you want to know what is happening on the level of histological level then I can refer to Raghavendra S. Jayesh and V. Dhinakarsamy article on osteointegration (listed below as an attachment) where they showed histological steps where osteointegration become a bond between titanium and bone see fig 3 (two parts)osseointegration mechanism .

Based on many experience and literature review I would like to define osteointegration As

A bio-mechanical bond (a new terminology by me ) which explains both the mechanical and biological properties

Sincerely

Dr.K.A.Galil.Professor of Dentistry DDS.,D.Oral & Maxillofacial Surgery ,PH.D,FAGD.,FADI.,Cert.Periodontist(Royal College of Dental Surgeons of Ontario))

Departments of Periodontics,Orthodontics and Clinical Anatomy .

Schulich School Of Medicine and Dentistry. University of Western Ontario London,Ontario.

vist us at www.drgalil.ca

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