Is there any software free available to represent different fragments in pharmacophore like HBD,HBA, VdW region, hydrophobic region ?

Which Scopus Journal provides the most affordable fees?

"PUBLISHING IN A SCOPUS JOURNAL" Researchers are now at a cross road. The critical need to publish in a Scopus or ISI, etc journal is ever vital. Journal Publication fees must be submitted....

10 August 2024 8,621 1 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,403 2 View

What condition of Kirat Rai's participation in politics before and now in Nepal?

The political participation of the Kirat Rai community in Nepal has evolved significantly over time: Historical Context Historically, the Kirat Rai people, like many indigenous groups in Nepal,...

05 August 2024 5,950 1 View

Could you please suggest methods to compare free protein and immobolized protein binding properties?

I have an antibody binding generic protein and I need to compare its activity in a free and immobolized form. I understand that there are a number of methods to determine Kd value of a free...

05 August 2024 5,311 0 View

Where can I find free research instruments for Nursing?

for eg. transition shock scale

01 August 2024 5,998 0 View

Why do open and free science in a world where science is not open and free?

Because I have realized that the world tends more and more to do open and free science and there is a trend more and more to choose free databases, free tools and open access platforms.

01 August 2024 10,046 1 View

My cfDNA extraction protocol using silica beads works with plasma collected in COD SAGM bags but not with plasma collected in K2 EDTA tubes. Why so?

I am currently performing cell-free DNA (cfDNA) extraction from plasma using an in-house developed kit that employs silica-coated magnetic beads. My protocol works effectively with plasma obtained...

28 July 2024 3,559 0 View

Do you know of any online international conferences that offer free discussions?

Do you know of any online international conferences that offer free discussions? I am looking for examples in the field of molecular ecology and DIY biology.

28 July 2024 6,501 0 View

What does the difference \lambda_j - \lambda_{j+1} represent in relation to the conjugate partition of \lambda?

For a partition of an integer \lambda, what does the difference \lambda_j - \lambda_{j+1} represent in relation to the conjugate partition, , with \lambda_j being the j-th element of \lambda?

23 July 2024 8,008 1 View

Why binding energy is in positive number after performing mmpbsa?

I performed mmpbsa of protein-protein complex simulation on gromacs. My binding free energy is +166781. This complex is stable when experimentally produced in wet lab. In index.ndx I grouped...

19 July 2024 4,120 5 View

Sk. Abdul Amin

Yes, there are a number of open-source softwares to perfrom pharmacophore mapping. A few of this are-

(a) PharmMap (http://www.meilerlab.org/index.php/research/show?w_text_id=32)

(b) Pharmer for efficient and exact pharmacophore search (http://pharmer.sourceforge.net)

Thanking you,

Aamin

Farhana Desai

ChemAxon's Calculator (cxcalc) is a command line program in Marvin Beans

Dear Dr. Desai,

I don’t think that ChemAxon's Calculator (cxcalc) may solve the problem raised by Mamta Thakur. Does ChemAxon's Calculator (cxcalc) is use for pharmacophore mapping????

i think that can be done with their inbuild plugin

Thats very good. But the software did not claim for that.

Check it https://chemaxon.com/products/calculators-and-predictors