http://en.cnki.com.cn/Article_en/CJFDTOTAL-HCHX20050200K.htm

Synthesis and Characterization of 6-Maleimido Caproic Acid: 《Chinese Journal of Synthetic Chemistry》 2005-02

Maleimido caproic acid, was synthesized by the reaction of 6-aminocaproic acid and maleic anhydride at room temperature in 5.0 h by using acetic anhydride and sodium acetate as a catalyst, and the yield reached 90.34%. The structure was characterized by 1H NMR, IR and LC-MS.

http://en.cnki.com.cn/Journal_en/B-B016-HCHX-2005-02.htm

Synthesis of 6-Maleimidocaproic Acid Maleic anhydride (29.4 g, 0.3 mol) and 6-aminocaproic acid (39.35 g, 0.3 mol) were refluxed in glacial acetic acid (900 mL) for 16 h. Acetic anhydride (30.6 g, 0.3 mol) was added dropwise over a period of 2 hand reflux was continued for 1 h. The acetic acid was removed under vacuum at 70 °C to yield yellow syrup which solidified. The material was chromatographed over silica using dichloromethane-methanol-acetic acid (100:5:1) affording a crystalline solid. Fig. S6.

Electronic Supplementary Information for

Functional 2-methylene-1,3-dioxepane copolymer: a versatile platform to

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Tongjiang Caia, Yangjun Chena, Yin Wanga, Haibo Wanga, Xiangsheng Liua, Qiao Jin*a, Seema

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