Maybe, we should also consider:

Neem (Azadirachta indica): Neem has a long history in traditional medicine for its antimicrobial and anti-inflammatory properties. Research has explored its effectiveness in treating periodontal diseases and as an ingredient in mouthwashes and toothpastes for its ability to reduce plaque formation and gingivitis.Tea Tree Oil: Derived from the leaves of Melaleuca alternifolia, tea tree oil has been studied for its antimicrobial properties against oral pathogens. Its application in mouthwashes has shown promise in reducing gingival inflammation and dental plaque.Myrrh and Frankincense: These resins have historical uses in oral hygiene for their antimicrobial and healing properties. Current research is investigating their efficacy in treating oral ulcers and gingivitis, with preliminary studies suggesting benefits in reducing inflammation and promoting oral health.Turmeric: With its active compound curcumin, turmeric is being researched for its anti-inflammatory and antimicrobial effects. Studies are examining its role in treating gingivitis, periodontitis, and oral cancers, with some formulations being incorporated into gels and mouth rinses.Propolis: A resinous substance produced by bees, propolis has garnered attention for its broad antimicrobial activities. Its application in dental care is being explored, particularly in wound healing, reducing plaque, and treating periodontal diseases.

I'm sure it's time to start use natural products .

Im researching with pineapple,papain, and citrics finguis